Skip to main content
East Cobb Med Spa

Published sources

References

The comparisons are easier to follow with the relatives’ full names and the original experiments close at hand.

A starting pair

The peritonitis and macrophage comparison is the argumentative centre of this collection. Read it beside the intestinal-cell and PepT1 paper: the cytokine findings make a useful, awkward pairing. Reading their disagreement is more satisfying than treating either as the final word on KPV.

Relatives, tissues and models

For the family background, there is a review of alpha-MSH and related tripeptides. For experiments that depend especially on preparation, compare Lys-D-Pro-Val, KdPT and the synthetic dimer (CKPV)2.

The complete list follows.

  1. Dissection of the anti-inflammatory effect of the core and C-terminal (KPV) alpha-melanocyte-stimulating hormone peptides ↗
  2. Alpha-melanocyte-stimulating hormone and related tripeptides: biochemistry, antiinflammatory and protective effects in vitro and in vivo, and future perspectives for the treatment of immune-mediated inflammatory diseases ↗
  3. PepT1-mediated tripeptide KPV uptake reduces intestinal inflammation ↗
  4. Melanocortin-derived tripeptide KPV has anti-inflammatory potential in murine models of inflammatory bowel disease ↗
  5. Alpha-melanocyte-related tripeptide, Lys-d-Pro-Val, ameliorates endotoxin-induced nuclear factor kappaB translocation and activation ↗
  6. The tripeptide KdPT protects from intestinal inflammation and maintains intestinal barrier function ↗
  7. Alpha-melanocyte-stimulating hormone, MSH 11-13 KPV and adrenocorticotropic hormone signalling in human keratinocyte cells ↗
  8. Lysine-Proline-Valine peptide mitigates fine dust-induced keratinocyte apoptosis and inflammation ↗
  9. Antimicrobial effects of alpha-MSH peptides ↗
  10. The synthetic melanocortin (CKPV)2 exerts anti-fungal and anti-inflammatory effects against Candida albicans vaginitis via inducing macrophage M2 polarization ↗