# References

> East Cobb Med Spa references — The East Cobb Med Spa reading list: published studies and a review on KPV, related tripeptides, skin cells, intestinal inflammation and microbes.

**Published sources**

The comparisons are easier to follow with the relatives’ full names and the original experiments close at hand.

## A starting pair

The [peritonitis and macrophage comparison](https://pubmed.ncbi.nlm.nih.gov/12750433/) is the argumentative centre of this collection. Read it beside the [intestinal-cell and PepT1 paper](https://pubmed.ncbi.nlm.nih.gov/18061177/): the cytokine findings make a useful, awkward pairing. Reading their disagreement is more satisfying than treating either as the final word on KPV.

## Relatives, tissues and models

For the family background, there is a [review of alpha-MSH and related tripeptides](https://pubmed.ncbi.nlm.nih.gov/18612139/). For experiments that depend especially on preparation, compare [Lys-D-Pro-Val](https://pubmed.ncbi.nlm.nih.gov/11256945/), [KdPT](https://pubmed.ncbi.nlm.nih.gov/21741932/) and [the synthetic dimer (CKPV)2](https://pubmed.ncbi.nlm.nih.gov/23457491/).

The complete list follows.

## References

[1] Dissection of the anti-inflammatory effect of the core and C-terminal (KPV) alpha-melanocyte-stimulating hormone peptides https://pubmed.ncbi.nlm.nih.gov/12750433/
[2] Alpha-melanocyte-stimulating hormone and related tripeptides: biochemistry, antiinflammatory and protective effects in vitro and in vivo, and future perspectives for the treatment of immune-mediated inflammatory diseases https://pubmed.ncbi.nlm.nih.gov/18612139/
[3] PepT1-mediated tripeptide KPV uptake reduces intestinal inflammation https://pubmed.ncbi.nlm.nih.gov/18061177/
[4] Melanocortin-derived tripeptide KPV has anti-inflammatory potential in murine models of inflammatory bowel disease https://pubmed.ncbi.nlm.nih.gov/18092346/
[5] Alpha-melanocyte-related tripeptide, Lys-d-Pro-Val, ameliorates endotoxin-induced nuclear factor kappaB translocation and activation https://pubmed.ncbi.nlm.nih.gov/11256945/
[6] The tripeptide KdPT protects from intestinal inflammation and maintains intestinal barrier function https://pubmed.ncbi.nlm.nih.gov/21741932/
[7] Alpha-melanocyte-stimulating hormone, MSH 11-13 KPV and adrenocorticotropic hormone signalling in human keratinocyte cells https://pubmed.ncbi.nlm.nih.gov/15102092/
[8] Lysine-Proline-Valine peptide mitigates fine dust-induced keratinocyte apoptosis and inflammation https://pubmed.ncbi.nlm.nih.gov/40073467/
[9] Antimicrobial effects of alpha-MSH peptides https://pubmed.ncbi.nlm.nih.gov/10670585/
[10] The synthetic melanocortin (CKPV)2 exerts anti-fungal and anti-inflammatory effects against Candida albicans vaginitis via inducing macrophage M2 polarization https://pubmed.ncbi.nlm.nih.gov/23457491/

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I read about KPV and its relatives in published research at East Cobb Med Spa, an essay collection with no medical business and no medical advice.